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hydrocodone bitartrate and acetaminophen
Dosage Form: tablet
Zydone®
(Hydrocodone Bitartrate and
Acetaminophen Tablets, USP)
CIII
Rx only

WARNING

Hepatotoxicity

Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen containing product.

Zydone Description

Zydone (hydrocodone bitartrate and acetaminophen tablets), for oral administration, contain hydrocodone bitartrate and acetaminophen in the following strengths:

Hydrocodone Bitartrate, USP	5 mg
Acetaminophen, USP	400 mg

Hydrocodone Bitartrate, USP	7.5 mg
Acetaminophen, USP	400 mg

Hydrocodone Bitartrate, USP	10 mg
Acetaminophen, USP	400 mg

In addition, each tablet contains the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, crospovidone, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid. The 5 mg/400 mg strength contains FD&C Yellow No. 10; 7.5 mg/400 mg contains FD&C Blue No. 2; and 10 mg/400 mg contains FD&C Red No. 40.

Zydone Tablets meet USP Dissolution Test 1.

Hydrocodone bitartrate is an opioid analgesic and antitussive an

Zerit Pediatrics

Generic Name: stavudine (Oral route)

STAV-ue-deen

Oral route(Capsule;Powder for Solution)

Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported. Fatal lactic acidosis has been reported in pregnant women who received the combination of stavudine and didanosine with other antiretroviral agents. The combination of stavudine and didanosine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk. Fatal and nonfatal pancreatitis have occurred during therapy when stavudine was part of a combination regimen that included didanosine .

Commonly used brand name(s)

In the U.S.

Zerit

In Canada

Zerit Pediatrics

Available Dosage Forms:

Capsule
Powder for Suspension
Powder for Solution

Therapeutic Class: Antiretroviral Agent

Pharmacologic Class: Nucleoside Reverse Transcriptase Inhibitor

Uses For Zerit Pediatrics

Stavudine is used in combination with other anti-virus medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Stavudine will not cure or prevent HIV infection or AIDS. It helps to keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease.

Stavudine will not keep you or your child from spreading HIV to other people. People who receive this medicine may continue to have the problems usually related to AIDS or HIV disease.

This medicine is available only with your doctor's prescription.

Before Using Zerit Pediatrics

In deciding to use a medicine, the risks of t

Zanaflex

Pronunciation: tye-ZAN-i-deen
Generic Name: Tizanidine
Brand Name: Zanaflex

Zanaflex is used for:

Treating muscle spasms. It may also be used for other conditions as determined by your doctor.

Zanaflex is a skeletal muscle relaxant. It works by blocking nerves that stimulate muscles to contract.

Do NOT use Zanaflex if:

you are allergic to any ingredient in Zanaflex
you are taking ciprofloxacin or fluvoxamine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zanaflex:

Some medical conditions may interact with Zanaflex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have liver or kidney problems or prostate problems

Some MEDICINES MAY INTERACT with Zanaflex. Tell your health care provider if you are taking any other medicines, especially any of the following:

Acyclovir, antiarrhythmics (eg, amiodarone, mexiletine, propafenone), cimetidine, famotidine, fluvoxamine, hormonal contraceptives (eg, birth control pills), quinolone antibiotics (eg, ciprofloxacin), ticlopidine, verapamil, or zileuton because they may increase the risk of Zanaflex's side effects

Zorbtive

Generic Name: somatropin (soe ma TROE pin)
Brand Names: Genotropin, Genotropin Miniquick, Humatrope, Norditropin, Norditropin Cartridge, Norditropin FlexPro Pen, Norditropin Nordiflex Pen, Nutropin, Nutropin AQ, Omnitrope, Saizen, Serostim, Tev-tropin, Zorbtive

What is somatropin?

Somatropin is a form of human growth hormone. Human growth hormone is important in the body for the growth of bones and muscles.

Somatropin is used to treat growth failure in children and adults who lack natural growth hormone, and in those with chronic kidney failure, Noonan syndrome, Turner syndrome, Prader-Willi syndrome, short stature at birth with no catch-up growth, and other causes. Somatropin is also used to prevent severe weight loss in people with AIDS, or to treat short bowel syndrome.

Somatropin may also be used for purposes not listed in this medication guide.

What is the most important information I should know about somatropin?

Before you receive somatropin, tell your doctor about all your past and present medical conditions, especially allergies, trauma, surgery, diabetes, cancer, breathing problems, liver or kidney disease, scoliosis, high blood pressure, pancreas disorder, underactive thyroid, or a brain tumor.

Also tell your doctor about all other medications you use, especially steroids or diabetes medications. Your dosages of these medicines may need to be changed when you start using somatropin. Do not stop using a steroid suddenly or change any of your medication doses without your doctor's advice.

If you have Prader-Willi syndrome and are using somatropin, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or increased snoring.

Call your doctor at once if you have sudden and severe pain in your upper stomach with nausea and vomiting, fast hea

Zevalin

Generic Name: Ibritumomab Tiuxetan
Class: Antineoplastic Agents
VA Class: AN600
Chemical Name: N - [2 - [bis(carboxymethyl)amino] - 3 - (4 - isothiocyanatophenyl)propyl] - N - [2 - [bis(carboxymethyl)amino]propyl] glycine conjugate dimer disulfide with mouse monoclonal IDEC-Y2B8k-chain anti-(human CD20 (antigen)) (mouse monoclonal IDEC-Y2B8 ?1-chain) immuglobulin G1
CAS Number: 206181-63-7

Experience of Supervising Clinician
Use only by qualified clinicians experienced in the safe use and handling of radionuclides.¹ ⁷

Rituximab-related Infusion Reactions
Fatalities have occurred within 24 hours following rituximab infusion, an essential component of the ibritumomab tiuxetan therapeutic regimen.¹ ²
Fatalities were associated with an infusion reaction symptom complex that included hypoxia, pulmonary infiltrates, acute respiratory distress syndrome, MI, ventricular fibrillation, and/or cardiogenic shock.¹
Approximately 80% of fatal infusion reactions occurred with initial infusion of rituximab.¹ ⁴
If severe infusion-related effects develop, discontinue rituximab, indium In 111 ibritumomab tiuxetan, and yttrium Y 90 ibritumomab tiuxetan, and initiate appropriate therapy.¹ (See Infusion-related Effects under Cautions.)

Cytopenias
Most patients receiving the ibritumomab tiuxetan therapeutic regimen develop prolonged and severe cytopenias.

Zofran

Generic Name: ondansetron (Injection route)

on-DAN-se-tron hye-droe-KLOR-ide

Commonly used brand name(s)

In the U.S.

Zofran

Available Dosage Forms:

Solution

Therapeutic Class: Antiemetic

Pharmacologic Class: Ondansetron

Uses For Zofran

Ondansetron injection is used to prevent the nausea and vomiting that may occur after treatment with cancer medicines (chemotherapy or radiation), including high-dose cisplatin. This medicine is also used to prevent and treat nausea and vomiting that may happen after surgery.

This medicine is available only with your doctor's prescription.

Before Using Zofran

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ondansetron injection in children. However, safety and efficacy have not been established in infants with cancer younger than 6 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific

Zarontin

Generic Name: ethosuximide (ETH oh SUX i mide)
Brand Names: Zarontin

What is Zarontin (ethosuximide)?

Ethosuximide is an anti-epileptic medication, also called an anticonvulsant.

Ethosuximide is used alone or in combination with other medications to treat absence seizures (also called "petit mal" seizures) in adults and children.

Ethosuximide may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Zarontin (ethosuximide)?

Ethosuximide can cause a decrease in many types of blood cells (white cells, red cells, platelets). Call your doctor at once if you have any unusual bleeding, weakness, or any signs of infection, even if these symptoms first occur after you have been using the medication for several months.

Ethosuximide may also cause liver damage. Call your doctor if you have symptoms such as loss of appetite, stomach pain, or jaundice (yellowing of the skin or eyes).

You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, depression, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Do not stop using ethosuximide without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using ethosuximide suddenly. You will need to use less and less before you stop the medication completely.

Contact your doctor if your seizures get worse or you have them more often while taking ethosuximide.

Wear a medical alert tag or carry an ID card stating

Zema Pak 13-Day

Generic Name: dexamethasone (oral) (dex a METH a sone)
Brand Names: Baycadron, Dexamethasone Intensol, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, Dexpak Jr. Taperpak, Zema Pak 10-Day, Zema Pak 13-Day, Zema Pak 6-Day

What is dexamethasone?

Dexamethasone is a steroid that prevents the release of substances in the body that cause inflammation.

Dexamethasone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Dexamethasone may also be used for purposes not listed in this medication guide.

What is the most important information I should know about dexamethasone?

You should not use this medication if you are allergic to dexamethasone, or if you have a fungal infection anywhere in your body.

Before taking dexamethasone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other diseases that can be affected by steroid use, and many other medicines that can interact with steroids.

Your steroid medication needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment.

Steroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication.

Do not receive a "liv

Zocor

Generic Name: simvastatin (Oral route)

sim-va-STAT-in

Commonly used brand name(s)

In the U.S.

Zocor

Available Dosage Forms:

Tablet
Tablet, Disintegrating

Therapeutic Class: Antihyperlipidemic

Pharmacologic Class: HMG-COA Reductase Inhibitor

Uses For Zocor

Simvastatin is used together with a proper diet to treat high cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems caused by clogged blood vessels such as heart attacks and strokes.

Simvastatin belongs to the group of medicines called HMG-CoA reductase inhibitors or "statins." It works to reduce the amount of cholesterol in the blood by blocking an enzyme that is needed to make cholesterol.

This medicine is available only with your doctor's prescription.

Before Using Zocor

Allergies

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of simvastatin in children 10 to 17 years of age. The safety and efficacy of simvastatin in children younger than 10 years of age have not been established.

Teenage girls taking simvastatin should be counseled on appropriate birth control methods to prevent pregnancy.

Zevalin In-111

Generic Name: ibritumomab (Intravenous route)

eye-bri-TOOM-oh-mab tye-UX-e-tan

Intravenous route(Solution)

Serious infusion reactions, including fatalities, have occurred within 24 hours of rituximab infusion, an essential component of the ibritumomab tiuxetan therapeutic regimen. Most fatal infusion reactions (80%) occurred with the first rituximab infusion. Administration also results in severe and prolonged cytopenias in most patients. The ibritumomab tiuxetan therapeutic regimen should not be administered to patients with 25% or greater lymphoma marrow involvement and/or impaired bone marrow reserve. Severe cutaneous and mucocutaneous reactions, some with fatal outcome, can occur with therapy. The dose of Y-90 ibritumomab tiuxetan should not exceed the absolute maximum allowable dose of 32 millicurie (1184 megabecquerels) .

Commonly used brand name(s)

In the U.S.

Zevalin In-111
Zevalin Y-90

Available Dosage Forms:

Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Monoclonal Antibody

Uses For Zevalin In-111

Ibritumomab injection is a monoclonal antibody. It is used together with another monoclonal antibody (rituximab) and one radioactive medication (Y-90). Ibritumomab is used to treat a type of cancer called non-Hodgkin's lymphoma (NHL) in patients who have never received any treatment and for those who have received other cancer medicines.

This medicine is to be administered only by or under the immediate supervision of your doctor.

Before Using Zevalin In-111

Allergies

Zolpidem

Dosage Form: tablet, film coated
FULL PRESCRIBING INFORMATION

Indications and Usage for Zolpidem

Zolpidem tartrate tablets are indicated for the short-term treatment of insomnia characterized by difficulties with sleep initiation. Zolpidem tartrate tablets have been shown to decrease sleep latency for up to 35 days in controlled clinical studies [see Clinical Studies (14)].

The clinical trials performed in support of efficacy were 4 to 5 weeks in duration with the final formal assessments of sleep latency performed at the end of treatment.

Zolpidem Dosage and Administration

The dose of Zolpidem tartrate tablets should be individualized.

Dosage in Adults

The recommended dose for adults is 10 mg once daily immediately before bedtime. The total Zolpidem tartrate tablets dose should not exceed 10 mg per day.

Special Populations

Elderly or debilitated patients may be especially sensitive to the effects of Zolpidem tartrate tablets. Patients with hepatic insufficiency do not clear the drug as rapidly as normal subjects. The recommended dose of Zolpidem tartrate tablets in both of these patient populations is 5 mg once daily immediately before bedtime [see Warningsand Precautions (5.6)].

Use With CNS Depressants

Dosage adjustment may be necessary when Zolpidem tartrate tablets are combined with other CNS depressant

Zometa

Pronunciation: ZOE-le-DRON-ik AS-id
Generic Name: Zoledronic Acid
Brand Name: Zometa

Zometa is used for:

Treating high blood calcium levels caused by cancer. It is also used with other medicines to treat patients with certain types of cancer. It may also be used for other conditions as determined by your doctor.

Zometa is a bisphosphonate. It works by decreasing the breakdown of bone. This reduces the amount of calcium that is released into the blood from bones and helps to lower your blood calcium level.

Do NOT use Zometa if:

you are allergic to any ingredient in Zometa or to any other bisphosphonate (eg, alendronate)
you have severe kidney problems and you also have a certain type of cancer (multiple myeloma) or cancer that has moved into the bones from other parts of the body
you are pregnant, planning to become pregnant, or are breast-feeding
you are taking another medicine that contains zoledronic acid or any other bisphosphonate (eg, alendronate)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zometa:

Some medical conditions may interact with Zometa. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

Zelboraf

Generic Name: vemurafenib (Oral route)

vem-ue-RAF-e-nib

Commonly used brand name(s)

In the U.S.

Zelboraf

Available Dosage Forms:

Tablet

Uses For Zelboraf

Vemurafenib is used to treat melanoma (a type of skin cancer) that has spread or that cannot be removed by surgery. It is only used if the melanoma cells have the BRAF V600E mutation. Your doctor will use a special test to look for this mutation. Vemurafenib belongs to the group of medicines called antineoplastics (cancer medicines).

This medicine is available only with your doctor's prescription.

Before Using Zelboraf

Allergies

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of vemurafenib in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of vemurafenib in the elderly. However, elderly patients are more likely to have unwanted effects (e.g., skin problems, decreased appetite, fast heartbeat, nausea, or swelling of the hands, feet, or legs) which may require caution in patients receiving vemurafenib.

Pregnancy

	Pregnancy C

Zervalx

Generic Name: l-methylfolate (L-METH il FOE late)
Brand Names: Deplin, Zervalx

What is Zervalx (l-methylfolate)?

Folate is a form of B vitamin that occurs naturally in many foods. Folic acid is the man-made form of folate that is added to processed foods or vitamin and mineral supplements. Folate is needed in the human body for production of red blood cells.

A lack (deficiency) of folate in the human body can be caused by certain diseases, by taking certain medications, or by not getting enough folate in your diet. Folate deficiency can lead to decreased red blood cells, or anemia.

L-methylfolate is a medical food for use in people who have conditions related to folate deficiency.

The Zervalx brand of l-methylfolate is used in the following situations:

in people who have high levels of a certain amino acid in their blood, a condition called hyperhomocysteinemia (HYE-per-HOE-moe-sis-tin-EE-mee-a). This condition can be related to folate deficiency or may be caused by receiving methotrexate (Rheumatrex, Trexall);
in women with high-risk pregnancies who need additional folate in their diets to prevent hyperhomocysteinemia; or
in people with certain types of anemia (a lack of red blood cells) that may be complicated by a folate deficiency.

The Deplin brand of l-methylfolate is used in the following situations:

in people with major depressive disorder who have folate deficiency. Deplin is used together with anti-depressant medications in people with major depressive disorder and low folate levels.
in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.

Deplin is not an antidepressant. However, it may enhance the effects of antidepressant medications.

L-methylfolate may also be used for other purposes not list

Zyflo CR Extended-Release Tablets

Pronunciation: zye-LOO-ton
Generic Name: Zileuton
Brand Name: Zyflo CR

Zyflo CR Extended-Release Tablets are used for:

Preventing and treating asthma in patients 12 years old and older. It may also be used for other conditions as determined by your doctor.

Zyflo CR Extended-Release Tablets are a leukotriene synthesis inhibitor. It works by blocking the formation of a substance called leukotriene, which helps to decrease certain asthma and allergy symptoms.

Do NOT use Zyflo CR Extended-Release Tablets if:

you are allergic to any ingredient in Zyflo CR Extended-Release Tablets
you have liver disease or abnormal liver function tests
you are taking astemizole, pimozide, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zyflo CR Extended-Release Tablets:

Some medical conditions may interact with Zyflo CR Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of liver problems (eg, hepatitis) or symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine)
if you have a history of mental or mood problems (eg, depression) or suicida

Zincfrin

Generic Name: phenylephrine and zinc ophthalmic (fen ill EFF rin and zink off THAL mick)
Brand Names: Zincfrin

What is Zincfrin (phenylephrine and zinc ophthalmic)?

Phenylephrine ophthalmic causes decongestion in the eye by constricting blood vessels in the eye.

Zinc is used as an astringent to gently clear proteins and mucous from the outer surface of the eye.

Phenylephrine and zinc ophthalmic is used to relieve redness, burning, irritation, and dryness of the eye caused by wind, sun, smoke, smog, and other minor irritants.

Phenylephrine and zinc ophthalmic may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Zincfrin (phenylephrine and zinc ophthalmic)?

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

Apply light pressure to the inside corner of the eye (near the nose) after each drop to prevent the fluid from draining down the tear duct.

Do not use phenylephrine and zinc ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen.

Do not use phenylephrine and zinc ophthalmic if you have glaucoma, except under the direction of your doctor.

Use caution when driving, operating machinery, or performing other hazardous activities. Phenylephrine and zinc ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.

What should I discuss with my healthcare provider before using Zincfrin (phenylephrine and zinc ophthalmic)?

Do not use phenylephrine and zinc ophtha

Zithromax Suspension

Pronunciation: ay-ZITH-roe-MYE-sin
Generic Name: Azithromycin
Brand Name: Zithromax

Zithromax Suspension is used for:

Treating mild to moderate infections caused by certain bacteria. It may also be used alone or with other medicines to treat or prevent certain infections in persons with advanced HIV infection. It may also be used for other conditions as determined by your doctor.

Zithromax Suspension is a macrolide antibiotic. It slows the growth of, or sometimes kills, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Do NOT use Zithromax Suspension if:

you are allergic to any ingredient in Zithromax Suspension, to other macrolide antibiotics (eg, erythromycin), or to ketolide antibiotics (eg, telithromycin)
you have a history of liver problems or yellowing of the skin or eyes caused by any doseform (eg, tablets, suspension, injection) of Zithromax Suspension
you are taking cisapride, dofetilide, dronedarone, nilotinib, pimozide, propafenone, or tetrabenazine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zithromax Suspension:

Some medical conditions may interact with Zithromax Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant,

Zomig Nasal Spray

Dosage Form: nasal spray, metered
FULL PRESCRIBING INFORMATION

Indications and Usage for Zomig Nasal Spray

Acute Treatment of Migraine Attacks

Zomig Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults.

Important Limitations

ZOMIG should only be used where a clear diagnosis of migraine has been established. If a patient has no response for the first migraine attack treated with ZOMIG, the diagnosis of migraine should be reconsidered before ZOMIG is administered to treat any subsequent attacks.

ZOMIG is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine [see Contraindications (4.6)].

Safety and effectiveness of ZOMIG have not been established for cluster headache, which is present in an older, predominantly male population.

Zomig Nasal Spray Dosage and Administration

Acute Treatment of Migraine Attacks

Administer one dose of Zomig Nasal Spray 5 mg for the treatment of acute migraine. If the headache returns, the dose may be repeated after 2 hours. The effectiveness of a second dose has not been established in placebo-controlled trials. The maximum daily dose should not exceed 10 mg in any 24-hour period.

In controlled clinical trials, single doses of 5 mg of zolmitriptan nasal spray were administered into one nostril and were effective for the treatment of acute migraines in adults.

Individuals may vary in response to Zomig Nasal Spray. The pharmacokinetics of a 5 mg nasal spray dose is similar to the 5 mg oral formulations. Doses lower than 5 mg can only be achieved through the use of an oral formulation. The choice of dose, and route of administ

Ziac

Pronunciation: BIS-oh-PROE-lol/HYE-droe-KLOR-oh-THYE-a-zide
Generic Name: Bisoprolol/Hydrochlorothiazide
Brand Name: Ziac

Ziac is used for:

Treating high blood pressure.

Ziac is a beta-blocker and diuretic combination. The beta-blocker works by slowing down the heartbeat, helping the heart beat more regularly, and reducing the amount of work the heart has to do. The diuretic increases the elimination of excess fluid, which helps to decrease blood pressure.

Do NOT use Ziac if:

you are allergic to any ingredient in Ziac or to a sulfonamide medicine (eg, sulfamethoxazole, probenecid, glyburide)
you have uncontrolled heart failure, heart block, a very slow heart rate, or shock caused by serious heart problems
you are unable to urinate
you are taking another beta-blocker (eg, propranolol), dofetilide, or mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ziac:

Some medical conditions may interact with Ziac. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have asthma, bronchitis, lung disease (eg, chronic obstructive pulmonary disease [COPD]), diabetes, gout, an overactive thyroid,

Z-Tuss AC Liquid

Pronunciation: KLOR-fen-IR-a-meen/KOE-deen
Generic Name: Chlorpheniramine/Codeine
Brand Name: Examples include Notuss-AC and Z-Tuss AC

Z-Tuss AC Liquid is used for:

Relieving runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Z-Tuss AC Liquid is an antihistamine and narcotic cough suppressant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Z-Tuss AC Liquid if:

you are allergic to any ingredient in Z-Tuss AC Liquid or any other codeine- or morphine-related medicine (eg, oxycodone)
you have severe high blood pressure, severe heart blood vessel disease, angle-closure glaucoma, or peptic ulcers
you are unable to urinate or are having an asthma attack
you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Z-Tuss AC Liquid:

Some medical conditions may interact with Z-Tuss AC Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription